argS [2019-08-12 11:53:23]

arginyl-tRNA synthetase, universally conserved protein

locus: BSU_37330

pI: 5.11

mw: 62.55 kDa

protein length: 556 aa

gene length: 1671 bp

function: translation

product: arginyl-tRNA synthetase

essential: yes

ec: 6.1.1.19

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.10|Aminoacyl-tRNA synthetases]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
• [category|SW 6|Groups of genes] → [category|SW 6.5|Universally conserved proteins]

Gene

Coordinates: 3,833,650 3,835,320

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg) (according to Swiss-Prot)

Protein family

• [SW|Class-I aminoacyl-tRNA synthetase family] (according to UniProt)

Structure

• [PDB|3FNR] (from ''Campylobacter jejuni'', 39% identity, 56% similarity)

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Additional information

• [SW|universally conserved protein]

Expression and Regulation

Operons

• genes: [gene|83721D87607FE6448C2C0D17E401C87C57A05AF8|argS]
  description: [Pubmed|9353933]

• genes: [gene|D71F54220FCC2B687857F53F53584D6CB90650CD|ywiB]-[gene|83721D87607FE6448C2C0D17E401C87C57A05AF8|argS]
  description: [Pubmed|22383849]

additional information

• the mRNA is cleaved by [protein|BAB297D18F94FFA67B8D12A684AB4D1BCDFB4981|RNase III] [PubMed|26883633]

References

• 9353933,26883633